Extractos y links a abstracts de estudios sobre efectos de spirulina en casos de anemia, desnutrición infantil y durante el embarazo.
# EMBARAZO:
1) Tres estudios en mujeres embarazadas en India
(Fuente: http://
1) Tres estudios en mujeres embarazadas en India
(Fuente: http://
- Effect of Spirulina supplementation on Vitamin A status during pregnancy (March 1995)
- Effect of Spirulina Supplementation on Vitamin A status During Pregnancy and Lactation (September 2001)
- Effect of Supplementation of Spirulina on the Nutritional Status of Pregnant Women (2001)
2) Spirulina superfood consumed during pregnancy blocks cadmium from damaging developing babies - Natural News Science
http://m.naturalnews.com/news/
# ANEMIA:
1)
Spirulina platensis feeding inhibited the anemia- and leucopenia-induced lead and cadmium in rats.
2009 Journal of hazardous materials
2)
The effects of Spirulina on anemia and immune function in senior citizens.
2011 Cellular & molecular immunologyhttp://m.naturalnews.com/news/
- Spirulina (Arthrospira) Protects Against Cadmium-Induced Teratogenic Damage in Mice. 2011 Journal of medicinal food
- Spirulina maxima and its protein extract protect against hydroxyurea-teratogenic insult in mice. 2009 Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Relacionado al anterior:
- A randomized double-blind, placebo-controlled study to establish the effects of spirulina in elderly Koreans. Annals of nutrition & metabolism
CLAVE:
# SPIRULINA PARA REHABILITACION DE NIÑOS CON DESNUTRICION
# SPIRULINA PARA REHABILITACION DE NIÑOS CON DESNUTRICION
"Nutrition rehabilitation of undernourished children utilizing Spiruline and Misola"
Jacques Simpore1,2, Fatoumata Kabore1, Frederic Zongo1, Deleli Dansou1,
Augustin Bere1, Salvatore Pignatelli2, Daniela M Biondi3, Giuseppe Ruberto3
and Salvatore Musumeci*4,5
"At the end of the eight weeks of the treatment, nutritional status normalized for the majority of children (...) The index weight for age WAZ (weight for age z-score) at the end of our study allowed to confirm that severe malnutrition was corrected by this protocol of treatment, more significantly in the Misola plus Spiruline group."
Abstract
Background: Malnutrition constitutes a public health problem throughout the world and particularly in developing countries.
Aims: The objective of the study is to assess the impact of an elementary integrator composed of Spiruline (Spirulina platensis) and Misola (millet, soja, peanut) produced at the Centre Medical St Camille (CMSC) of Ouagadougou, Burkina Faso, on the nutritional status of undernourished children.
Materials and methods: 550 undernourished children of less than 5 years old were enrolled in this study, 455 showed severe marasma, 57 marasma of medium severity and 38 kwashiorkor plus marasma. We divided the children randomly into four groups: 170 were given Misola (731 ± 7 kcal/day), 170 were given Spiruline plus traditional meals (748 ± 6 kcal/day), 170 were given Spiruline plus Misola (767 ± 5 kcal/day). Forty children received only traditional meals (722 ± 8 kcal/day) and functioned as the control group. The duration of this study was eight weeks.
Results and Discussion: Anthropometrics and haematological parameters allowed us to appreciate both the nutritional and biological evolution of these children. The rehabilitation with Spiruline plus Misola (this association gave an energy intake of 767 ± 5 kcal/day with a protein assumption of 33.3 ± 1.2 g a day), both greater than Misola or Spiruline alone, seems to correct weight loss more quickly.
Conclusion: Our results indicate that Misola, Spiruline plus traditional meals or Spiruline plus Misola are all a good food supplement for undernourished children, but the rehabilitation by Spiruline plus Misola seems synergically favour the nutrition rehabilitation better than the simple addition of protein and energy intake.
Jacques Simpore1,2, Fatoumata Kabore1, Frederic Zongo1, Deleli Dansou1,
Augustin Bere1, Salvatore Pignatelli2, Daniela M Biondi3, Giuseppe Ruberto3
and Salvatore Musumeci*4,5
"At the end of the eight weeks of the treatment, nutritional status normalized for the majority of children (...) The index weight for age WAZ (weight for age z-score) at the end of our study allowed to confirm that severe malnutrition was corrected by this protocol of treatment, more significantly in the Misola plus Spiruline group."
Abstract
Background: Malnutrition constitutes a public health problem throughout the world and particularly in developing countries.
Aims: The objective of the study is to assess the impact of an elementary integrator composed of Spiruline (Spirulina platensis) and Misola (millet, soja, peanut) produced at the Centre Medical St Camille (CMSC) of Ouagadougou, Burkina Faso, on the nutritional status of undernourished children.
Materials and methods: 550 undernourished children of less than 5 years old were enrolled in this study, 455 showed severe marasma, 57 marasma of medium severity and 38 kwashiorkor plus marasma. We divided the children randomly into four groups: 170 were given Misola (731 ± 7 kcal/day), 170 were given Spiruline plus traditional meals (748 ± 6 kcal/day), 170 were given Spiruline plus Misola (767 ± 5 kcal/day). Forty children received only traditional meals (722 ± 8 kcal/day) and functioned as the control group. The duration of this study was eight weeks.
Results and Discussion: Anthropometrics and haematological parameters allowed us to appreciate both the nutritional and biological evolution of these children. The rehabilitation with Spiruline plus Misola (this association gave an energy intake of 767 ± 5 kcal/day with a protein assumption of 33.3 ± 1.2 g a day), both greater than Misola or Spiruline alone, seems to correct weight loss more quickly.
Conclusion: Our results indicate that Misola, Spiruline plus traditional meals or Spiruline plus Misola are all a good food supplement for undernourished children, but the rehabilitation by Spiruline plus Misola seems synergically favour the nutrition rehabilitation better than the simple addition of protein and energy intake.
CLAVE:
#Spirulina in the fight against malnutrition: Assessment and Prospects (2011): Ver sintesis web: Ver PDF
An introduction to the nutritional and therapeutic properties of spirulina, and an overview of the many studies on the topic.
For many years, health agencies and NGOs have used spirulina in developing countries to successfully treat tens of thousands of children suffering from mild or moderate malnutrition.
CLAVE:
# SPIRULINA CASE STUDY (2006)
#Spirulina in the fight against malnutrition: Assessment and Prospects (2011): Ver sintesis web: Ver PDF
An introduction to the nutritional and therapeutic properties of spirulina, and an overview of the many studies on the topic.
For many years, health agencies and NGOs have used spirulina in developing countries to successfully treat tens of thousands of children suffering from mild or moderate malnutrition.
Despite such positive results and the
many studies proving its efficacy, spirulina is still not recognised by
the intergovernmental agencies and major NGOs concerned with the fight
against malnutrition.
o change this situation, ANTENNA publishes and sends out Spirulina in the fight against malnutrition: Assessment and prospects.
It is an introduction to the nutritional and therapeutic properties of
spirulina, and an overview of the many studies on the topic. With this
document, we demand that these organisations acknowledge the potential
of spirulina and include it in their programmes to fight against
chronic malnutrition
CLAVE:
# SPIRULINA CASE STUDY (2006)
Ver PDF: En el resumen ejecutivo (página 13) está la justificacion de uso de spirulina contra la desnutricion y sintesis. Otras páginas clave: 45-47 , 71 y 78-79
CLAVE:
Algae as an Approach to Combat Malnutrition in Developing Countries By Christophe Hug and Denis von der Weid, Antenna Technologies Foundation, 2012
# PARA NIÑOS CON ANEMIA
POSOLOGÍA DE LA ESPIRULINA
Fuente: “Spirulina de Burkina” www.spirulineburkina.org/es/
POSOLOGÍA DE LA ESPIRULINA
Fuente: “Spirulina de Burkina” www.spirulineburkina.org/es/
Desnutrición infantil, anemia:
Se han constatado efectos notables partiendo de dosis que varían según el peso del niño entre 1 y 5g/día.
La duración de la cura cotidiana será del orden de 4 a 6 semanas y, los primeros resultados aparecen normalmente al cabo de pocos días.
Al principio de la comida, cuando se va a comer, se añade a una pequeña cantidad de papilla, de salsa o de arroz, una cucharadilla más o menos llena de espirulina, para que el niño se la tome antes de empezar a comer.
En general, los niños en edad de alimentarse, pasados los primeros momentos de sorpresa por ser un alimento nuevo, la toleran bien y la asimilan con facilidad. En el caso contrario, hay que proceder con la sonda gástrica con una mezcla de espirulina y agua.
Lo que se constata más a menudo:
-Disminución de los edemas: entre 5 y 10 días
-Aparece la “sonrisa-respuesta”: en 8 a 13 días.
-Gana peso significativo desde el primer día (fuera Kwashiorkor) (de media 20g/día)
-Aumento de la tasa de hemoglobina al cabo de una o dos semanas.
-Aumento de los marcadores biológicos de la MPE: prealbúmina y transferina (por tanto buen valor nutritivo de la espirulina).
Además de la salud del niño, el balance económico de la utilización de la espirulina para un centro de rehabilitación nutricional (CREN) es muy interesante, ya que permite, no sólo la recuperación del niño más rápidamente que con las harinas tradicionales enriquecidas, sino también la economía de complementos vitamínicos y hierro de origen químico.
Salud preventiva de los adultos y de los deportistas, personas mayores, mujeres embarazadas, mujeres en lactancia: proceder por curas de 3 semanas a razón de 5g/día, sin interrupción (1 a 2 cucharadillas/día en la comida).
Se han constatado efectos notables partiendo de dosis que varían según el peso del niño entre 1 y 5g/día.
La duración de la cura cotidiana será del orden de 4 a 6 semanas y, los primeros resultados aparecen normalmente al cabo de pocos días.
Al principio de la comida, cuando se va a comer, se añade a una pequeña cantidad de papilla, de salsa o de arroz, una cucharadilla más o menos llena de espirulina, para que el niño se la tome antes de empezar a comer.
En general, los niños en edad de alimentarse, pasados los primeros momentos de sorpresa por ser un alimento nuevo, la toleran bien y la asimilan con facilidad. En el caso contrario, hay que proceder con la sonda gástrica con una mezcla de espirulina y agua.
Lo que se constata más a menudo:
-Disminución de los edemas: entre 5 y 10 días
-Aparece la “sonrisa-respuesta”: en 8 a 13 días.
-Gana peso significativo desde el primer día (fuera Kwashiorkor) (de media 20g/día)
-Aumento de la tasa de hemoglobina al cabo de una o dos semanas.
-Aumento de los marcadores biológicos de la MPE: prealbúmina y transferina (por tanto buen valor nutritivo de la espirulina).
Además de la salud del niño, el balance económico de la utilización de la espirulina para un centro de rehabilitación nutricional (CREN) es muy interesante, ya que permite, no sólo la recuperación del niño más rápidamente que con las harinas tradicionales enriquecidas, sino también la economía de complementos vitamínicos y hierro de origen químico.
Salud preventiva de los adultos y de los deportistas, personas mayores, mujeres embarazadas, mujeres en lactancia: proceder por curas de 3 semanas a razón de 5g/día, sin interrupción (1 a 2 cucharadillas/día en la comida).
# SPIRULINA EN NIÑOS EN EDAD ESCOLAR
Contribution of supplementation by spirulina to the performance of school children in an introductory course in Dakar (Senegal)
...Over these 60 days, the students took a daily dose of 2 grams of spirulina mixed with 10g of honey to make the taste acceptable...The sample size was a total of 549 schoolchildren: 273 (49.72%) were girls, and 276 (50.28%) boys. The mean age was 91 months [90.29-91.71]....
Effect of Spirulina on Anthropometry and Bio-Chemical Parameters in School Children, 2013 (ver aquí articulo completo) Realizado en 150 niños, un estudio similar a éste podría hacerse en embarazadas.
"There was a significant increase in anthropometric measurements and Hemoglobin, serum ferrtin, serum zinc, serum protein and serum albumin levels in the study sample after 6 months. Conclusion: The anthropometric and bio-chemical parameters improved after the use of spirulina"
# MÁS INVESTIGACIONES SOBRE SPIRULINA Y RECUPERACION DE LA MALNUTRICION (solo referencias y abstracts)http://www.spirulinasource.
# GENERAL: Spirulina in Clinical Practice: Evidence-Based Human Applications. Spirulina explained: Here's what you need to know about this
# GENERAL: Spirulina in Clinical Practice: Evidence-Based Human Applications. Spirulina explained: Here's what you need to know about this
# BIBLIOGRAFIA COMPLETA HASTA 2006 BibliographieSPI_2006 muestra la bibliografía completa, con resumen de los artículos científicos sobre la espirulina entre 1966 y 2006, disponible en http://www.antenna.ch/
Abajo el extracto de los estudios realizados durante el embarazo en ratas, que figuran en dicho archivo:
123: Chamorro G, Salazar S, Fav
ila-Castillo L, Steele C, Salazar M.
Reproductive and peri- and postnatal evaluation of Spirulina maxima in mice.
J Appl Phycol 9, No 2 (1997) 107-112.
PMID: pas
pdf: Chamorro G 1997.pdf
mots-clés article: $toxicity-evaluation, $reproductive-toxicology, $s
ingle-cellproteins, $Spirulina.mots-clés Antenna: £spirulina-maxima, £d£.
résumé:
Spirulina maxima, provided by Sosa Texcoco Company (México City), was administered to mice of
both sexes in a fertility study, at concentrations of 0, 10, 20 and 30% incorporated into the diet. Males
were fed for nine weeks while females, for two weeks, and feeding continued during the mating period and gestation. On the other hand, in a peri- and postnatal study, the alga was given only to females at the same concentrations from day 15 of gestation until day 21 post-partum. Treatments were not associated with any adverse effect on reproductive performance, pregnancy rate, number of corpora lutea, resorptions or number of live or dead fetuses. There was no increase in the number of abnormal pups at caesarean section. Length of gestation, parturition status, and litter values were unaffected by treatment. However, there was a statistically significant reduction in bodyweight and survival rate on postnatal days 0–4 at the high dose group in the peri- and postnatal study. The reproductive performance of F1 generation was normal in all groups. We conclude that S. maxima is not toxic to reproduction.
ila-Castillo L, Steele C, Salazar M.
Reproductive and peri- and postnatal evaluation of Spirulina maxima in mice.
J Appl Phycol 9, No 2 (1997) 107-112.
PMID: pas
pdf: Chamorro G 1997.pdf
mots-clés article: $toxicity-evaluation, $reproductive-toxicology, $s
ingle-cellproteins, $Spirulina.mots-clés Antenna: £spirulina-maxima, £d£.
résumé:
Spirulina maxima, provided by Sosa Texcoco Company (México City), was administered to mice of
both sexes in a fertility study, at concentrations of 0, 10, 20 and 30% incorporated into the diet. Males
were fed for nine weeks while females, for two weeks, and feeding continued during the mating period and gestation. On the other hand, in a peri- and postnatal study, the alga was given only to females at the same concentrations from day 15 of gestation until day 21 post-partum. Treatments were not associated with any adverse effect on reproductive performance, pregnancy rate, number of corpora lutea, resorptions or number of live or dead fetuses. There was no increase in the number of abnormal pups at caesarean section. Length of gestation, parturition status, and litter values were unaffected by treatment. However, there was a statistically significant reduction in bodyweight and survival rate on postnatal days 0–4 at the high dose group in the peri- and postnatal study. The reproductive performance of F1 generation was normal in all groups. We conclude that S. maxima is not toxic to reproduction.
125: Chamorro G, Salazar M.
Teratogenic study of Spirulina in mice.
Arch Latinoam Nutr 1990;40:86-94
pdf: Chamorro G 1990.pdf PAS
The embryotoxic and fetotoxic potential of Spirulina was investigated in mice. The algae was given to pregnant animals at the levels of 0, 10, 20 and 30 g/100 in the diet through days 7-13, 1-13 and 1-19 of gestation. On day 19, the rats were sacrificed, and the uterine horns were examined for live, dead and resorbed fetuses. The live fetuses were we ighed and examined for external malformations and either skeletal or visceral abnormalities. With the litter as the unit of analysis and when the total number of fetuses affected was considered, no significant difference was found in the number of
resorbed or malformed among groups. These results indicate that the feeding of pregnant mice with
algae, up to a dietary level of 30 g/100, did not evoke any signs of embryotoxic effects. The Spirulina
levels tested in this study represent exaggeration over any anticipated human consumption.
388: Kapoor R, Mehta U.
Supplementary effect of spirulina on hematological status of rats during pregnancy and lactation.
Plant Foods Hum Nutr. 1998;52(4):315-24.
PMID: 10426118
pdf: Kapoor R 1998.papier
mots-clés article: $Blue-green-alga; $Hematological-response; $Protein; $Spirulina; $Supplementation; $Wheat-gluten.
The effect of Spirulina on iron status was assessed based on hemoglobin, packed cell volume, serum
iron, total iron binding capacity and ferritin levels of rats during pregnancy and lactation. Rats were fed 5 different kinds of diets (casein, Spirulina, wheat gluten, Spirulina + wheat gluten, Spirulina without additional vitamins and minerals) each providing 22 percent protein. Diets containing Spirulina alone or in combination with wheat gluten resulted in significantly higher iron storage and hemoglobin contents than casein and wheat gluten diets during the first half
of pregnancy and lactation. Wheat gluten diet result in the smallest increase in hemoglobin levels and iron stores compared to other diets. The values of serum iron and iron binding capacity remained unchanged with different diets. Spirulina appears to be effective in improving the iron status of rats during pregnancy and lactation.
Teratogenic study of Spirulina in mice.
Arch Latinoam Nutr 1990;40:86-94
pdf: Chamorro G 1990.pdf PAS
The embryotoxic and fetotoxic potential of Spirulina was investigated in mice. The algae was given to pregnant animals at the levels of 0, 10, 20 and 30 g/100 in the diet through days 7-13, 1-13 and 1-19 of gestation. On day 19, the rats were sacrificed, and the uterine horns were examined for live, dead and resorbed fetuses. The live fetuses were we ighed and examined for external malformations and either skeletal or visceral abnormalities. With the litter as the unit of analysis and when the total number of fetuses affected was considered, no significant difference was found in the number of
resorbed or malformed among groups. These results indicate that the feeding of pregnant mice with
algae, up to a dietary level of 30 g/100, did not evoke any signs of embryotoxic effects. The Spirulina
levels tested in this study represent exaggeration over any anticipated human consumption.
388: Kapoor R, Mehta U.
Supplementary effect of spirulina on hematological status of rats during pregnancy and lactation.
Plant Foods Hum Nutr. 1998;52(4):315-24.
PMID: 10426118
pdf: Kapoor R 1998.papier
mots-clés article: $Blue-green-alga; $Hematological-response; $Protein; $Spirulina; $Supplementation; $Wheat-gluten.
The effect of Spirulina on iron status was assessed based on hemoglobin, packed cell volume, serum
iron, total iron binding capacity and ferritin levels of rats during pregnancy and lactation. Rats were fed 5 different kinds of diets (casein, Spirulina, wheat gluten, Spirulina + wheat gluten, Spirulina without additional vitamins and minerals) each providing 22 percent protein. Diets containing Spirulina alone or in combination with wheat gluten resulted in significantly higher iron storage and hemoglobin contents than casein and wheat gluten diets during the first half
of pregnancy and lactation. Wheat gluten diet result in the smallest increase in hemoglobin levels and iron stores compared to other diets. The values of serum iron and iron binding capacity remained unchanged with different diets. Spirulina appears to be effective in improving the iron status of rats during pregnancy and lactation.
390: Kapoor R, Mehta U.
Effect of supplementation of blue green alga (Spirulina) on outcome of pregnancy in rats.
Plant Foods Hum Nutr 1993;43:29-35.
PMID: 8464842
pdf: Kapoor R 1993a.pdf PAS
To study the supplementary effect of Spirulina, pregnant rats were fed 5 different kinds of diets (casein, Spirulina, wheat gluten, Spirulina + wheat gluten, Spirulina without additional vitamins and minerals), each providing 22% protein during the period of pregnancy. The outcome of the pregnancy was assessed from litter and dams’ weight and litter size. Maternal weight gain was found to be maximum with Spirulina+wheat gluten and least with the wheat glutehn diet. Rats receiving Spirulina containing diets produced significantly (p<0.05) higher litter size than those receiving casein and wheat gluten. In spite of having higher litter size, Spirulina containing diet groups produced pups with birth weights comparable to those of casein. Spirulina appears to be a good dietary supplement during pregnancy
Effect of supplementation of blue green alga (Spirulina) on outcome of pregnancy in rats.
Plant Foods Hum Nutr 1993;43:29-35.
PMID: 8464842
pdf: Kapoor R 1993a.pdf PAS
To study the supplementary effect of Spirulina, pregnant rats were fed 5 different kinds of diets (casein, Spirulina, wheat gluten, Spirulina + wheat gluten, Spirulina without additional vitamins and minerals), each providing 22% protein during the period of pregnancy. The outcome of the pregnancy was assessed from litter and dams’ weight and litter size. Maternal weight gain was found to be maximum with Spirulina+wheat gluten and least with the wheat glutehn diet. Rats receiving Spirulina containing diets produced significantly (p<0.05) higher litter size than those receiving casein and wheat gluten. In spite of having higher litter size, Spirulina containing diet groups produced pups with birth weights comparable to those of casein. Spirulina appears to be a good dietary supplement during pregnancy
829: Tulliez J, Bories G, Boudène C, Février C.
Les hydrocarbures des algues spirulines: nature, étude du devenir de l’heptadécane chez le rat et le porc.
[Hydrocarbons of the spiruline algae: nature,
metabolism of heptadecane by rats and swine].
Ann Nutr Aliment. 1975;29(6):563-72.
PMID: 824998
pdf: Tulliez J 1975.pdf PAS
Les hydrocarbures des algues spirulines: nature, étude du devenir de l’heptadécane chez le rat et le porc.
[Hydrocarbons of the spiruline algae: nature,
metabolism of heptadecane by rats and swine].
Ann Nutr Aliment. 1975;29(6):563-72.
PMID: 824998
pdf: Tulliez J 1975.pdf PAS
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